Research

A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death

A Cell-Permeant Mimetic of NMN Activates SARM1 ...

Understanding SARM1: An Enzyme with Key Roles in Cellular Processes Biochemistry: Exploring the Building Blocks of Life SARM1 is an enzyme that regulates axonal degeneration and utilizes NAD. CZ-48 is...

A Cell-Permeant Mimetic of NMN Activates SARM1 ...

Understanding SARM1: An Enzyme with Key Roles in Cellular Processes Biochemistry: Exploring the Building Blocks of Life SARM1 is an enzyme that regulates axonal degeneration and utilizes NAD. CZ-48 is...

Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment

Age-related disruption of the proteome and acet...

Title: Study Finds Mitochondrial-Targeted Drugs May Help Reverse Aging Effects on Heart Proteins Introduction: A recent study has investigated the effects of aging on protein abundance and acetylation in mouse...

Age-related disruption of the proteome and acet...

Title: Study Finds Mitochondrial-Targeted Drugs May Help Reverse Aging Effects on Heart Proteins Introduction: A recent study has investigated the effects of aging on protein abundance and acetylation in mouse...

Oral nicotinamide mononucleotide (NMN) to treat chronic insomnia: protocol for the multicenter, randomized, double-blinded, placebo-controlled trial

Oral nicotinamide mononucleotide (NMN) to treat...

Title: Potential New Treatment for Chronic Insomnia: Study Investigates the Effects of Nicotinamide Mononucleotide (NMN) Introduction: Insomnia is a common sleep disorder that affects a significant portion of the population....

Oral nicotinamide mononucleotide (NMN) to treat...

Title: Potential New Treatment for Chronic Insomnia: Study Investigates the Effects of Nicotinamide Mononucleotide (NMN) Introduction: Insomnia is a common sleep disorder that affects a significant portion of the population....

Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice: comparison with exercise

Nicotinamide mononucleotide (NMN) supplementati...

Understanding the Impact of Maternal Obesity on Offspring Metabolism and Potential Interventions Introduction: Maternal overnutrition increases the risk of long-term metabolic dysfunction in offspring. Exercise improves metabolism by upregulating mitochondrial...

Nicotinamide mononucleotide (NMN) supplementati...

Understanding the Impact of Maternal Obesity on Offspring Metabolism and Potential Interventions Introduction: Maternal overnutrition increases the risk of long-term metabolic dysfunction in offspring. Exercise improves metabolism by upregulating mitochondrial...

Treatment of inflammatory bowel disease: Potential effect of NMN on intestinal barrier and gut microbiota

Treatment of inflammatory bowel disease: Potent...

Article Summary: Title: Nicotinamide Mononucleotide (NMN) Shows Potential in Treating Inflammatory Bowel Disease (IBD) Introduction Inflammatory bowel disease (IBD) is a chronic condition characterized by intestinal inflammation and various predisposing...

Treatment of inflammatory bowel disease: Potent...

Article Summary: Title: Nicotinamide Mononucleotide (NMN) Shows Potential in Treating Inflammatory Bowel Disease (IBD) Introduction Inflammatory bowel disease (IBD) is a chronic condition characterized by intestinal inflammation and various predisposing...

Characterization of Two NMN Deamidase Mutants as Possible Probes for an NMN Biosensor

Characterization of Two NMN Deamidase Mutants a...

Article Summary: Title: Identification of Inactive Mutants of NMN Deamidase as Molecular Recognition Elements for an NMN-Specific Biosensor Introduction: Nicotinamide mononucleotide (NMN) is an important intermediate in the production of...

Characterization of Two NMN Deamidase Mutants a...

Article Summary: Title: Identification of Inactive Mutants of NMN Deamidase as Molecular Recognition Elements for an NMN-Specific Biosensor Introduction: Nicotinamide mononucleotide (NMN) is an important intermediate in the production of...

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