NMN and DNA Damage

NMN and DNA Damage

NMN (nicotinamide mononucleotide) is a supplement that has gained a lot of attention in recent years due to its potential anti-aging effects. One of the key benefits of NMN is its ability to repair DNA damage, which is crucial for maintaining optimal health and preventing age-related diseases. In this blog post, we will explore NMN's ability to repair DNA damage and how it can benefit your health.

What is DNA damage?

DNA damage is a natural process that occurs as we age or due to exposure to environmental factors such as radiation, chemicals, or toxins. This damage can cause mutations in our DNA, leading to various health problems such as cancer, neurodegenerative diseases, and premature aging. Fortunately, our bodies have mechanisms to repair DNA damage, but as we age, these mechanisms become less efficient, leading to an accumulation of damage over time.

How NMN repairs DNA damage

NMN is a molecule that plays a crucial role in energy production and DNA repair. It works by boosting levels of NAD+ (nicotinamide adenine dinucleotide), a coenzyme that is essential for many cellular processes, including DNA repair. NAD+ levels decline with age, which can impair the body's ability to repair DNA damage, leading to age-related diseases.

Studies have shown that NMN supplementation can increase NAD+ levels in the body, which in turn can activate enzymes that repair DNA damage. One study conducted on mice found that NMN supplementation led to improved DNA repair and reduced the incidence of age-related diseases such as cancer and liver damage.

Benefits of NMN for DNA repair

The ability of NMN to repair DNA damage has several benefits for overall health and longevity. Here are a few:

  1. Reduces the risk of age-related diseases: As we age, the risk of developing diseases such as cancer, Alzheimer's, and Parkinson's increases. NMN's ability to repair DNA damage can reduce the risk of these diseases by maintaining the integrity of our DNA.

  2. Slows down the aging process: DNA damage is one of the primary causes of aging. By repairing DNA damage, NMN can slow down the aging process and improve overall health and well-being.

  3. Improves cellular energy production: NMN's role in energy production can help improve cellular function, leading to better overall health and vitality.


NMN is a supplement that has gained popularity due to its potential anti-aging effects. Its ability to repair DNA damage is one of the key benefits of this supplement, which can improve overall health and reduce the risk of age-related diseases. By increasing NAD+ levels in the body, NMN can activate enzymes that repair DNA damage, leading to improved cellular function and longevity. If you're looking for a supplement that can benefit your health and well-being, Reversal NMN is a third-party tested 99% pure NMN supplement that may be worth considering.


  1. Scheibye-Knudsen, M., Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T. M., Wang, J., ... & Wilson, M. A. (2014). A high-fat diet and NAD+ activate Sirt1 to rescue premature aging in cockayne syndrome. Cell metabolism, 20(5), 840-855. doi: https://doi.org/10.1016/j.cmet.2014.10.005

  2. Mills, K. F., Yoshida, S., Stein, L. R., Grozio, A., Kubota, S., Sasaki, Y., ... & Imai, S. (2016). Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell metabolism, 24(6), 795-806. doi: https://doi.org/10.1016/j.cmet.2016.09.013

  3. Gomes, A. P., Price, N. L., Ling, A. J., Moslehi, J. J., Montgomery, M. K., Rajman, L., ... & Sinclair, D. A. (2013). Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell, 155(7), 1624-1638. doi: https://doi.org/10.1016/j.cell.2013.11.037

  4. Fang, E. F., Scheibye-Knudsen, M., Chua, K. F., Mattson, M. P., & Bohr, V. A. (2016). NAD+ in aging: molecular mechanisms and translational implications. Trends in molecular medicine, 22(8), 641-655. doi: https://doi.org/10.1016/j.molmed.2016.06.005

  5. Das, A., Huang, G. X., Bonkowski, M. S., Longchamp, A., Li, C., Schultz, M. B., ... & Sinclair, D. A. (2018). Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging. Cell, 173(1), 74-89. doi: https://doi.org/10.1016/j.cell.2018.02.008

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