Why I Stopped Taking NMN

Why I Stopped Taking NMN


In this article, we delve into the reasons behind my decision to stop taking Nicotinamide Mononucleotide (NMN), a popular supplement often touted for its anti-aging benefits. While NMN has gained considerable attention for its potential health benefits, it's important to explore both sides of the coin.

Background on NMN

NMN is a derivative of niacin, a type of Vitamin B3, and plays a crucial role in the production of NAD+, a coenzyme essential for cellular metabolism and energy production. Its popularity surged due to studies suggesting it could reverse some aging markers and improve healthspan. Research published in journals like Cell and Nature has pointed to its potential in enhancing cellular energy levels and repairing DNA damage, which are common issues as the body ages.

Initial Attraction to NMN

Like many, the allure of NMN came from its promise of anti-aging effects. The scientific community's interest in its potential to enhance longevity and improve various age-related issues made it an appealing supplement. High-profile endorsements from researchers at institutions like Harvard University further fueled the public's interest. Articles in The New York Times and Scientific American have covered the growing fascination with NMN and its purported benefits.

Experiences While Taking NMN

During the period of taking NMN, there were observations and experiences worth noting. Initially, there was a noticeable increase in energy levels and an overall sense of well-being. However, as time progressed, these benefits seemed to plateau. There were also concerns about the lack of long-term studies on NMN, as most research has been short-term or conducted on animal models. An article in The Journal of Clinical Investigation highlighted the need for more comprehensive human studies to understand the long-term effects of NMN supplementation.

Moreover, some personal side effects began to emerge. Although mild, they included digestive discomfort and insomnia, which raised concerns about the supplement's overall impact on my health. Discussions with healthcare professionals and further reading into the subject, including insights from Mayo Clinic and Johns Hopkins Medicine, suggested that these side effects, while not universal, were not uncommon among NMN users.

The cost of NMN supplementation also became a significant factor. With regular use, the expenses accumulated, leading to a reevaluation of its cost-effectiveness, especially in the absence of clear long-term benefits. Financial considerations, coupled with the uncertain long-term health impact, contributed significantly to the decision to stop taking NMN.

Emerging Research and Concerns

Despite initial enthusiasm, emerging research began to highlight potential concerns associated with long-term NMN use. Recent studies, including those published in ScienceDirect and The Lancet, have started to present a different perspective on NMN, focusing on its long-term effects and potential risks. Concerns have been raised about the possibility of NMN affecting insulin sensitivity and lipid metabolism, suggesting that its impact on metabolic processes might not be entirely beneficial. Furthermore, some scientists have raised questions about the effectiveness of orally administered NMN, as its bioavailability and ability to effectively increase NAD+ levels in humans remain subjects of debate.

Personal Reasons for Discontinuing NMN

The decision to stop taking NMN was influenced by a combination of factors. The emerging research raising concerns about long-term usage was a significant factor. Additionally, the personal side effects experienced, though mild, suggested that the supplement might not be as benign as initially thought. The lack of noticeable long-term benefits, despite consistent use, also played a role. Another critical consideration was the cost of maintaining a regular NMN supplementation regime, which seemed less justifiable given the uncertain benefits and potential risks.

Moreover, a shift in health philosophy towards more natural and holistic approaches to health and longevity influenced the decision. This shift emphasized the importance of diet, exercise, and lifestyle over supplementation as primary means of maintaining health and well-being.

Alternative Approaches to Health and Longevity

After stopping NMN, the focus shifted to alternative methods and lifestyle choices for promoting health and longevity. This included adopting a more balanced diet rich in antioxidants and nutrients, engaging in regular physical activity, and incorporating mindfulness and stress reduction techniques into daily life. Exploring other supplements, such as Omega-3 fatty acids and probiotics, which have more established track records and research supporting their benefits, became part of the new regimen.

Emphasis was also placed on getting adequate sleep, maintaining social connections, and engaging in activities that promote mental and emotional well-being. These lifestyle choices are backed by research from institutions like the Centers for Disease Control and Prevention and the World Health Organization, highlighting their importance in overall health and longevity.


The decision to stop taking NMN was not taken lightly. It stemmed from a holistic view of health and well-being, considering the latest scientific research, personal health experiences, and a commitment to sustainable and safe health practices. This experience highlights the importance of continuous learning and adaptation in the pursuit of health and underscores the need for more comprehensive research into supplements like NMN.

Final Thoughts

It's essential to remember that individual responses to supplements like NMN can vary greatly. What works for one person may not work for another. Therefore, it's crucial to consult with a healthcare provider before starting or stopping any supplement regimen. Personal health decisions should always be made based on a combination of scientific research, personal experiences, and professional advice, with an understanding that one size does not fit all in the realm of health and wellness.

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